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Are there cases where treatment is not recommended

Thus, the need for a therapy that can alleviate the social and economic burden that presents itself with debilitating and recurring soft tissue injuries is apparent

Existing studies have shown that the main features of depression are abnormal neurotransmitter levels in patients, abnormal function of the hypothalamic-pituitary-adrenal (HPA) axis, hormonal imbalance in the organism with inflammation and oxidative stress, neurotrophic factors, tryptophan metabolism, and the occurrence of gut microbiota-related diseases, as shown in Figure 1